Clinical Trials

ONC-403-001

A Two-Part Study of TB-403 in Pediatric Subjects with Relapsed or Refractory Medulloblastoma, Neuroblastoma, Ewing Sarcoma, or Alveolar Rhabdomyosarcoma.
OPEN

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NMTRC014

NMTT- Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine DFMO)
OPEN

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NMTRC012

PEDS-PLAN – Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
OPEN

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NMTRC011

A Phase I Trial of Tolcapone and Oxaliplatin in Patients with Relapsed or Refractory Neuroblastoma
OPEN

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NMTRC003B

A Phase II Preventative Trial of DFMO as a Single Agent in Patients with High Risk Neuroblastoma in Remission
CLOSED

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NMTRC009

Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers
OPEN

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NMTRC010

A Phase I/II Trial of DFMO in Combination with Bortezomib in Patients with Relapsed or Refractory Neuroblastoma
OPEN

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V0706

A Phase II Trial of Nifurtimox for Refractory or Relapsed Neuroblastoma or Medulloblastoma
OPEN TO THE FOLLOWING GROUPS: RELAPSE NEUROBLASTOMA MEDULLOBLASTOMA

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NMTRC001

A Feasibility Trial Using Molecular-Guided Therapy for the Treatment of Patients with Refractory or Recurrent Neuroblastoma
CLOSED

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NMTRCPG007

A Phase II, Open-label, Multi-center, Pilot Study of Erivedge (Vismodegib) in the Treatment of Pediatric Patients with Refractory Pontine Glioma
CLOSED

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NMTRC002

A Phase I Trial for Refractory or Relapsed Neuroblastoma with DFMO Along and in Combination with Etoposide
CLOSED

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NMTRC008

A Feasibility Trial using Molecular-Guided Therapy for the Treatment of Patients with Relapsed and Refractory Childhood Cancer
CLOSED

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TPI-287-11

A Phase 1 Trial of TPI 287 as a Single Agent and in Combination with Temozolomide in Patients with Refractory or Recurrent Neuroblastoma or Medulloblastoma
CLOSED

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NMTRC001P

A Pilot Trial Using Molecular-Guided Therapy in Patients With Refractory or Recurrent Neuroblastoma
CLOSED

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V0610

A Phase I Trial of Nifurtimox for Relapsed or Refractory Neuroblastoma
CLOSED

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NMTRC004

A Phase I/II Trial of TPI 287 in Patients with Refractory or Recurrent Neuroblastoma and Medulloblastoma
CLOSED

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NMTRC005

A Randomized, Phase I/II trial of Irinotecan and Temozolomide compared to Irinotecan and Temozolomide in Combination with TPI 287 in Patients with Primary Refractory or Early Relapsed Neuroblastoma
CLOSED

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